IT Quiz Answer – Dec 12, 2024
Here is the answer to our weekly Intelligent Thursday quiz!
Pop Quiz: December 12, 2024
A 61-year-old female reports with rectal bleeding, muscle aches, and fatigue. She’s been taking the first-line COVID treatment nirmatrelvir / ritonavir for 4 days. Which of her medications have a drug-drug interaction with nirmatrelvir / ritonavir that should have been addressed before she began taking nirmatrelvir / ritonavir?
A. Liraglutide
B. Metformin
C. Metoprolol succinate
D. Rivaroxaban
Check your answer!
The correct answer is D. Rivaroxaban
Explanation:
Gastrointestinal bleeding is always a risk factor with the use of direct oral anticoagulants (DOACs for short).
She is taking liraglutide 1.8 mg / day for diabetes, metformin 1000 mg / day for diabetes, metoprolol succinate 100 mg / day for hypertension and rate control, and rivaroxaban 15 mg / day for nonvalvular atrial fibrillation.
Use of the University of Liverpool’s drug-drug interaction checker, or another similar checker, should have helped you to determine that there are potential interactions with nirmatrelvir / ritonavir and rivaroxaban that should have been addressed prior to rivaroxaban being prescribed.
Liraglutide, metformin, and metoprolol succinate don’t interact with nirmatrelvir / ritonavir.
References:
Liverpool DDI Checker. March 2024.
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